Gene information
Official symbol TGFB1
Official full name transforming growth factor beta 1
Gene type protein-coding gene
Chromosome19q13.2
Alias symbolCED; TGFbeta
Previous symbolTGFB; DPD1
Gene familyTransforming growth factor beta family
Resources
Entrez Gene 7040
HGNC HGNC:11766
Ensembl ENSG00000105329
Vega OTTHUMG00000182760
UCSC uc002oqh.4
GO terms: 394 records
GO Description Category LogP Number of genes Detail
GO:0000018 regulation of DNA recombination GO Biological Processes -2.30127410 6 More
GO:0000165 MAPK cascade GO Biological Processes -7.43732657 14 More
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0001503 ossification GO Biological Processes -16.3087139 28 More
GO:0001558 regulation of cell growth GO Biological Processes -19.1123936 65 More
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001570 vasculogenesis GO Biological Processes -9.47667325 18 More
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0001837 epithelial to mesenchymal transition GO Biological Processes -7.70350405 17 More
GO:0001838 embryonic epithelial tube formation GO Biological Processes -6.74209917 20 More
GO:0001841 neural tube formation GO Biological Processes -5.20987525 16 More
GO:0001843 neural tube closure GO Biological Processes -4.06290305 13 More
GO:0001933 negative regulation of protein phosphorylation GO Biological Processes -19.8214973 59 More
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0002009 morphogenesis of an epithelium GO Biological Processes -21.4354199 71 More
GO:0002062 chondrocyte differentiation GO Biological Processes -4.35594728 7 More
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002246 wound healing involved in inflammatory response GO Biological Processes -8.11497800 5 More
GO:0002248 connective tissue replacement involved in inflammatory response wound healing GO Biological Processes -4.82387082 4 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0002637 regulation of immunoglobulin production GO Biological Processes -8.47662495 11 More
GO:0002639 positive regulation of immunoglobulin production GO Biological Processes -6.83160707 8 More
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0002694 regulation of leukocyte activation GO Biological Processes -32.0887020 60 More
GO:0002696 positive regulation of leukocyte activation GO Biological Processes -27.9249645 47 More
GO:0002697 regulation of immune effector process GO Biological Processes -33.2683521 48 More
GO:0002698 negative regulation of immune effector process GO Biological Processes -11.7829906 16 More
GO:0002699 positive regulation of immune effector process GO Biological Processes -18.3926498 29 More
GO:0002700 regulation of production of molecular mediator of immune response GO Biological Processes -19.7615296 26 More
GO:0002701 negative regulation of production of molecular mediator of immune response GO Biological Processes -8.92314992 9 More
GO:0002702 positive regulation of production of molecular mediator of immune response GO Biological Processes -12.4206918 17 More
GO:0002703 regulation of leukocyte mediated immunity GO Biological Processes -18.0432682 27 More
GO:0002705 positive regulation of leukocyte mediated immunity GO Biological Processes -8.38274670 14 More
GO:0002706 regulation of lymphocyte mediated immunity GO Biological Processes -13.7265777 21 More
GO:0002708 positive regulation of lymphocyte mediated immunity GO Biological Processes -8.31079168 13 More
GO:0002712 regulation of B cell mediated immunity GO Biological Processes -6.15575915 8 More
GO:0002714 positive regulation of B cell mediated immunity GO Biological Processes -6.30679788 7 More
GO:0002718 regulation of cytokine production involved in immune response GO Biological Processes -15.9157324 18 More
GO:0002719 negative regulation of cytokine production involved in immune response GO Biological Processes -9.55471636 12 More
GO:0002761 regulation of myeloid leukocyte differentiation GO Biological Processes -12.4818724 17 More
GO:0002763 positive regulation of myeloid leukocyte differentiation GO Biological Processes -8.56410954 10 More
GO:0002819 regulation of adaptive immune response GO Biological Processes -16.0189388 24 More
GO:0002821 positive regulation of adaptive immune response GO Biological Processes -12.1298033 16 More
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -14.6775052 22 More
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -10.1498702 14 More
GO:0002889 regulation of immunoglobulin mediated immune response GO Biological Processes -6.15575915 8 More
GO:0002891 positive regulation of immunoglobulin mediated immune response GO Biological Processes -6.30679788 7 More
GO:0003007 heart morphogenesis GO Biological Processes -18.8519524 49 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003018 vascular process in circulatory system GO Biological Processes -47.1670528 52 More
GO:0003170 heart valve development GO Biological Processes -11.9253160 20 More
GO:0003176 aortic valve development GO Biological Processes -8.77845673 13 More
GO:0003179 heart valve morphogenesis GO Biological Processes -9.26383069 16 More
GO:0003180 aortic valve morphogenesis GO Biological Processes -6.3383802 10 More
GO:0003205 cardiac chamber development GO Biological Processes -16.2154327 37 More
GO:0003206 cardiac chamber morphogenesis GO Biological Processes -17.7982686 34 More
GO:0003208 cardiac ventricle morphogenesis GO Biological Processes -12.9810396 22 More
GO:0003229 ventricular cardiac muscle tissue development GO Biological Processes -12.2262922 19 More
GO:0003231 cardiac ventricle development GO Biological Processes -15.0525208 31 More
GO:0005114 type II transforming growth factor beta receptor binding GO Molecular Functions -5.24494293 4 More
GO:0005125 cytokine activity GO Molecular Functions -54.7097150 57 More
GO:0005126 cytokine receptor binding GO Molecular Functions -41.4908940 50 More
GO:0005160 transforming growth factor beta receptor binding GO Molecular Functions -4.37707433 7 More
GO:0005796 Golgi lumen GO Cellular Components -14.6918478 18 More
GO:0005902 microvillus GO Cellular Components -2.78324946 11 More
GO:0006022 aminoglycan metabolic process GO Biological Processes -3.10129957 14 More
GO:0006026 aminoglycan catabolic process GO Biological Processes -3.11015029 4 More
GO:0006027 glycosaminoglycan catabolic process GO Biological Processes -2.38815415 5 More
GO:0006109 regulation of carbohydrate metabolic process GO Biological Processes -13.1742479 35 More
GO:0006163 purine nucleotide metabolic process GO Biological Processes -1.90037391 10 More
GO:0006468 protein phosphorylation GO Biological Processes -5.36604576 56 More
GO:0006753 nucleoside phosphate metabolic process GO Biological Processes -1.97459133 12 More
GO:0006913 nucleocytoplasmic transport GO Biological Processes -1.63729080 7 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0007162 negative regulation of cell adhesion GO Biological Processes -21.5212108 58 More
GO:0007167 enzyme-linked receptor protein signaling pathway GO Biological Processes -26.8285253 93 More
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway GO Biological Processes -16.7048742 60 More
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway GO Biological Processes -8.77828157 29 More
GO:0007179 transforming growth factor beta receptor signaling pathway GO Biological Processes -7.95704539 19 More
GO:0007507 heart development GO Biological Processes -29.3002557 91 More
GO:0007517 muscle organ development GO Biological Processes -15.8908392 49 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008083 growth factor activity GO Molecular Functions -26.3260872 31 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0009117 nucleotide metabolic process GO Biological Processes -2.02959005 12 More
GO:0009150 purine ribonucleotide metabolic process GO Biological Processes -1.73087600 10 More
GO:0009165 nucleotide biosynthetic process GO Biological Processes -1.85527211 8 More
GO:0009259 ribonucleotide metabolic process GO Biological Processes -1.59291266 10 More
GO:0009611 response to wounding GO Biological Processes -63.1714102 77 More
GO:0009617 response to bacterium GO Biological Processes -52.1760880 83 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009792 embryo development ending in birth or egg hatching GO Biological Processes -12.9988944 72 More
GO:0010563 negative regulation of phosphorus metabolic process GO Biological Processes -21.7837721 71 More
GO:0010575 positive regulation of vascular endothelial growth factor production GO Biological Processes -10.362168 13 More
GO:0010594 regulation of endothelial cell migration GO Biological Processes -41.8778170 72 More
GO:0010595 positive regulation of endothelial cell migration GO Biological Processes -28.3201829 45 More
GO:0010632 regulation of epithelial cell migration GO Biological Processes -42.8870194 81 More
GO:0010634 positive regulation of epithelial cell migration GO Biological Processes -29.2566722 52 More
GO:0010712 regulation of collagen metabolic process GO Biological Processes -14.4967625 19 More
GO:0010714 positive regulation of collagen metabolic process GO Biological Processes -7.35623750 7 More
GO:0010717 regulation of epithelial to mesenchymal transition GO Biological Processes -12.1292389 25 More
GO:0010718 positive regulation of epithelial to mesenchymal transition GO Biological Processes -11.466629 18 More
GO:0010720 positive regulation of cell development GO Biological Processes -17.713649 52 More
GO:0010762 regulation of fibroblast migration GO Biological Processes -4.05681596 5 More
GO:0010763 positive regulation of fibroblast migration GO Biological Processes -3.56180292 5 More
GO:0010799 regulation of peptidyl-threonine phosphorylation GO Biological Processes -2.65099080 7 More
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation GO Biological Processes -7.11509809 13 More
GO:0010935 regulation of macrophage cytokine production GO Biological Processes -5.69256069 5 More
GO:0014013 regulation of gliogenesis GO Biological Processes -13.3514185 26 More
GO:0014015 positive regulation of gliogenesis GO Biological Processes -11.0528361 19 More
GO:0014020 primary neural tube formation GO Biological Processes -5.01152693 15 More
GO:0014706 striated muscle tissue development GO Biological Processes -21.0654252 44 More
GO:0016331 morphogenesis of embryonic epithelium GO Biological Processes -7.49308957 23 More
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway GO Biological Processes -7.26381098 23 More
GO:0019216 regulation of lipid metabolic process GO Biological Processes -24.8423986 38 More
GO:0019693 ribose phosphate metabolic process GO Biological Processes -1.52492811 10 More
GO:0021915 neural tube development GO Biological Processes -7.57225811 24 More
GO:0022407 regulation of cell-cell adhesion GO Biological Processes -32.4337382 53 More
GO:0022408 negative regulation of cell-cell adhesion GO Biological Processes -15.9068791 40 More
GO:0022612 gland morphogenesis GO Biological Processes -7.35048069 19 More
GO:0030097 hemopoiesis GO Biological Processes -14.1443585 71 More
GO:0030111 regulation of Wnt signaling pathway GO Biological Processes -7.94227486 39 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030177 positive regulation of Wnt signaling pathway GO Biological Processes -5.04077211 10 More
GO:0030198 extracellular matrix organization GO Biological Processes -21.4880730 33 More
GO:0030203 glycosaminoglycan metabolic process GO Biological Processes -2.99315950 13 More
GO:0030212 hyaluronan metabolic process GO Biological Processes -2.63397233 5 More
GO:0030278 regulation of ossification GO Biological Processes -11.2759455 26 More
GO:0030308 negative regulation of cell growth GO Biological Processes -7.25826751 14 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030500 regulation of bone mineralization GO Biological Processes -10.1371537 13 More
GO:0030501 positive regulation of bone mineralization GO Biological Processes -4.86040077 10 More
GO:0030509 BMP signaling pathway GO Biological Processes -5.83413377 15 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0031091 platelet alpha granule GO Cellular Components -43.3287145 36 More
GO:0031093 platelet alpha granule lumen GO Cellular Components -40.0105787 31 More
GO:0031334 positive regulation of protein-containing complex assembly GO Biological Processes -8.84926570 16 More
GO:0031400 negative regulation of protein modification process GO Biological Processes -17.0986645 70 More
GO:0031663 lipopolysaccharide-mediated signaling pathway GO Biological Processes -14.0408172 12 More
GO:0031983 vesicle lumen GO Cellular Components -60.5757669 68 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0032355 response to estradiol GO Biological Processes -15.3711017 31 More
GO:0032386 regulation of intracellular transport GO Biological Processes -4.43340887 15 More
GO:0032388 positive regulation of intracellular transport GO Biological Processes -2.01592226 7 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0032570 response to progesterone GO Biological Processes -4.02622258 5 More
GO:0032660 regulation of interleukin-17 production GO Biological Processes -6.79373102 8 More
GO:0032740 positive regulation of interleukin-17 production GO Biological Processes -4.70812216 5 More
GO:0032801 receptor catabolic process GO Biological Processes -2.80517019 3 More
GO:0032881 regulation of polysaccharide metabolic process GO Biological Processes -7.60302561 13 More
GO:0032885 regulation of polysaccharide biosynthetic process GO Biological Processes -7.40593429 12 More
GO:0032965 regulation of collagen biosynthetic process GO Biological Processes -13.1192794 17 More
GO:0032967 positive regulation of collagen biosynthetic process GO Biological Processes -7.48167444 7 More
GO:0033135 regulation of peptidyl-serine phosphorylation GO Biological Processes -8.68560410 14 More
GO:0033138 positive regulation of peptidyl-serine phosphorylation GO Biological Processes -6.77396219 11 More
GO:0033157 regulation of intracellular protein transport GO Biological Processes -4.35957871 12 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0034103 regulation of tissue remodeling GO Biological Processes -21.5631413 32 More
GO:0034330 cell junction organization GO Biological Processes -7.96624809 49 More
GO:0034654 nucleobase-containing compound biosynthetic process GO Biological Processes -2.18989332 18 More
GO:0034713 type I transforming growth factor beta receptor binding GO Molecular Functions -4.31351457 5 More
GO:0034774 secretory granule lumen GO Cellular Components -58.3093741 66 More
GO:0035148 tube formation GO Biological Processes -7.32029616 23 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0035272 exocrine system development GO Biological Processes -2.77870822 4 More
GO:0035303 regulation of dephosphorylation GO Biological Processes -3.02544423 7 More
GO:0035304 regulation of protein dephosphorylation GO Biological Processes -2.33647794 5 More
GO:0035306 positive regulation of dephosphorylation GO Biological Processes -3.01689914 9 More
GO:0036314 response to sterol GO Biological Processes -7.24411974 11 More
GO:0038127 ERBB signaling pathway GO Biological Processes -2.50267494 8 More
GO:0040008 regulation of growth GO Biological Processes -30.7609323 104 More
GO:0040013 negative regulation of locomotion GO Biological Processes -30.7871461 81 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042060 wound healing GO Biological Processes -56.2139708 65 More
GO:0042306 regulation of protein import into nucleus GO Biological Processes -4.66703664 11 More
GO:0042307 positive regulation of protein import into nucleus GO Biological Processes -4.02622258 5 More
GO:0042326 negative regulation of phosphorylation GO Biological Processes -20.6187298 64 More
GO:0043009 chordate embryonic development GO Biological Processes -11.8113315 68 More
GO:0043062 extracellular structure organization GO Biological Processes -21.4370160 33 More
GO:0043112 receptor metabolic process GO Biological Processes -4.28720299 8 More
GO:0043114 regulation of vascular permeability GO Biological Processes -8.20071376 14 More
GO:0043117 positive regulation of vascular permeability GO Biological Processes -5.69256069 5 More
GO:0043254 regulation of protein-containing complex assembly GO Biological Processes -7.63830100 21 More
GO:0043255 regulation of carbohydrate biosynthetic process GO Biological Processes -8.87798147 21 More
GO:0043388 positive regulation of DNA binding GO Biological Processes -12.0675836 19 More
GO:0043405 regulation of MAP kinase activity GO Biological Processes -18.9267681 42 More
GO:0043406 positive regulation of MAP kinase activity GO Biological Processes -13.8261343 18 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0043491 protein kinase B signaling GO Biological Processes -12.2973970 11 More
GO:0043536 positive regulation of blood vessel endothelial cell migration GO Biological Processes -25.0316183 33 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0043550 regulation of lipid kinase activity GO Biological Processes -3.76907414 6 More
GO:0043551 regulation of phosphatidylinositol 3-kinase activity GO Biological Processes -3.24021630 5 More
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity GO Biological Processes -4.38579065 5 More
GO:0044089 positive regulation of cellular component biogenesis GO Biological Processes -10.7794496 56 More
GO:0045191 regulation of isotype switching GO Biological Processes -4.08159325 5 More
GO:0045216 cell-cell junction organization GO Biological Processes -2.57190963 16 More
GO:0045229 external encapsulating structure organization GO Biological Processes -21.3355594 33 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045598 regulation of fat cell differentiation GO Biological Processes -17.6607153 22 More
GO:0045599 negative regulation of fat cell differentiation GO Biological Processes -10.0272645 11 More
GO:0045637 regulation of myeloid cell differentiation GO Biological Processes -9.39364926 18 More
GO:0045639 positive regulation of myeloid cell differentiation GO Biological Processes -7.07849207 11 More
GO:0045649 regulation of macrophage differentiation GO Biological Processes -4.88843929 5 More
GO:0045651 positive regulation of macrophage differentiation GO Biological Processes -4.33413085 4 More
GO:0045661 regulation of myoblast differentiation GO Biological Processes -4.24103271 7 More
GO:0045662 negative regulation of myoblast differentiation GO Biological Processes -6.15988440 6 More
GO:0045685 regulation of glial cell differentiation GO Biological Processes -7.97684638 17 More
GO:0045687 positive regulation of glial cell differentiation GO Biological Processes -7.00526019 12 More
GO:0045778 positive regulation of ossification GO Biological Processes -4.90193440 11 More
GO:0045830 positive regulation of isotype switching GO Biological Processes -3.49817224 4 More
GO:0045834 positive regulation of lipid metabolic process GO Biological Processes -24.1838255 28 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045860 positive regulation of protein kinase activity GO Biological Processes -29.3929160 47 More
GO:0045911 positive regulation of DNA recombination GO Biological Processes -1.99479187 4 More
GO:0045912 negative regulation of carbohydrate metabolic process GO Biological Processes -5.15495164 11 More
GO:0045926 negative regulation of growth GO Biological Processes -11.4342361 38 More
GO:0045936 negative regulation of phosphate metabolic process GO Biological Processes -21.8424865 71 More
GO:0046034 ATP metabolic process GO Biological Processes -3.35244423 10 More
GO:0046822 regulation of nucleocytoplasmic transport GO Biological Processes -4.16168961 8 More
GO:0046824 positive regulation of nucleocytoplasmic transport GO Biological Processes -4.10947470 6 More
GO:0046849 bone remodeling GO Biological Processes -4.21089449 9 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0048514 blood vessel morphogenesis GO Biological Processes -39.8784810 93 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0048535 lymph node development GO Biological Processes -2.92766476 3 More
GO:0048545 response to steroid hormone GO Biological Processes -20.1914989 32 More
GO:0048568 embryonic organ development GO Biological Processes -17.1204114 64 More
GO:0048598 embryonic morphogenesis GO Biological Processes -22.1253699 83 More
GO:0048644 muscle organ morphogenesis GO Biological Processes -13.8992054 24 More
GO:0048660 regulation of smooth muscle cell proliferation GO Biological Processes -48.6624498 69 More
GO:0048661 positive regulation of smooth muscle cell proliferation GO Biological Processes -29.0732096 40 More
GO:0048729 tissue morphogenesis GO Biological Processes -31.7796969 96 More
GO:0048732 gland development GO Biological Processes -26.3979320 74 More
GO:0048738 cardiac muscle tissue development GO Biological Processes -21.5979622 44 More
GO:0048762 mesenchymal cell differentiation GO Biological Processes -16.1250183 37 More
GO:0048771 tissue remodeling GO Biological Processes -15.8777137 28 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050680 negative regulation of epithelial cell proliferation GO Biological Processes -26.5961536 48 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050714 positive regulation of protein secretion GO Biological Processes -15.7339081 32 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.9747849 34 More
GO:0050767 regulation of neurogenesis GO Biological Processes -15.7439029 55 More
GO:0050769 positive regulation of neurogenesis GO Biological Processes -12.1167088 37 More
GO:0050778 positive regulation of immune response GO Biological Processes -17.2528761 40 More
GO:0050864 regulation of B cell activation GO Biological Processes -7.98662389 16 More
GO:0050865 regulation of cell activation GO Biological Processes -40.6877761 71 More
GO:0050867 positive regulation of cell activation GO Biological Processes -31.2431659 51 More
GO:0050871 positive regulation of B cell activation GO Biological Processes -8.77049404 15 More
GO:0050920 regulation of chemotaxis GO Biological Processes -36.3269885 43 More
GO:0050921 positive regulation of chemotaxis GO Biological Processes -35.4880405 36 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051052 regulation of DNA metabolic process GO Biological Processes -4.01973325 42 More
GO:0051054 positive regulation of DNA metabolic process GO Biological Processes -3.76901955 13 More
GO:0051098 regulation of binding GO Biological Processes -15.8856010 30 More
GO:0051099 positive regulation of binding GO Biological Processes -11.1715489 31 More
GO:0051101 regulation of DNA binding GO Biological Processes -9.69427751 24 More
GO:0051129 negative regulation of cellular component organization GO Biological Processes -13.1016989 75 More
GO:0051153 regulation of striated muscle cell differentiation GO Biological Processes -11.0877013 23 More
GO:0051169 nuclear transport GO Biological Processes -1.63729080 7 More
GO:0051216 cartilage development GO Biological Processes -10.5011549 17 More
GO:0051222 positive regulation of protein transport GO Biological Processes -13.8994291 46 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0051249 regulation of lymphocyte activation GO Biological Processes -22.6120519 46 More
GO:0051251 positive regulation of lymphocyte activation GO Biological Processes -20.2181987 37 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051302 regulation of cell division GO Biological Processes -3.83250874 20 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051781 positive regulation of cell division GO Biological Processes -5.46648014 9 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051897 positive regulation of protein kinase B signaling GO Biological Processes -23.7578366 39 More
GO:0051960 regulation of nervous system development GO Biological Processes -17.2202851 64 More
GO:0051962 positive regulation of nervous system development GO Biological Processes -13.2580156 43 More
GO:0055008 cardiac muscle tissue morphogenesis GO Biological Processes -12.6682372 20 More
GO:0055010 ventricular cardiac muscle tissue morphogenesis GO Biological Processes -11.5275821 17 More
GO:0055086 nucleobase-containing small molecule metabolic process GO Biological Processes -1.91021091 13 More
GO:0060147 regulation of post-transcriptional gene silencing GO Biological Processes -6.75865733 12 More
GO:0060148 positive regulation of post-transcriptional gene silencing GO Biological Processes -3.60377864 4 More
GO:0060149 negative regulation of post-transcriptional gene silencing GO Biological Processes -7.60090654 9 More
GO:0060205 cytoplasmic vesicle lumen GO Cellular Components -59.3932782 67 More
GO:0060284 regulation of cell development GO Biological Processes -22.9455891 78 More
GO:0060312 regulation of blood vessel remodeling GO Biological Processes -5.39331932 6 More
GO:0060341 regulation of cellular localization GO Biological Processes -10.5933083 72 More
GO:0060389 pathway-restricted SMAD protein phosphorylation GO Biological Processes -7.32764136 8 More
GO:0060390 regulation of SMAD protein signal transduction GO Biological Processes -3.16367145 4 More
GO:0060391 positive regulation of SMAD protein signal transduction GO Biological Processes -4.11747892 4 More
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation GO Biological Processes -7.52187520 15 More
GO:0060395 SMAD protein signal transduction GO Biological Processes -3.01689914 9 More
GO:0060415 muscle tissue morphogenesis GO Biological Processes -13.8643925 23 More
GO:0060485 mesenchyme development GO Biological Processes -18.0238 46 More
GO:0060537 muscle tissue development GO Biological Processes -18.3336784 54 More
GO:0060562 epithelial tube morphogenesis GO Biological Processes -17.7630248 53 More
GO:0060606 tube closure GO Biological Processes -4.01197458 13 More
GO:0060828 regulation of canonical Wnt signaling pathway GO Biological Processes -5.69122875 29 More
GO:0060964 regulation of miRNA-mediated gene silencing GO Biological Processes -7.13447853 12 More
GO:0060965 negative regulation of miRNA-mediated gene silencing GO Biological Processes -7.86308931 9 More
GO:0060966 regulation of gene silencing by RNA GO Biological Processes -6.64085561 12 More
GO:0060967 negative regulation of gene silencing by RNA GO Biological Processes -7.60090654 9 More
GO:0061061 muscle structure development GO Biological Processes -23.2569142 77 More
GO:0061448 connective tissue development GO Biological Processes -12.1108226 21 More
GO:0062023 collagen-containing extracellular matrix GO Cellular Components -67.6170082 80 More
GO:0070167 regulation of biomineral tissue development GO Biological Processes -10.3239090 23 More
GO:0070168 negative regulation of biomineral tissue development GO Biological Processes -8.43961427 8 More
GO:0070169 positive regulation of biomineral tissue development GO Biological Processes -4.08950781 6 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0070374 positive regulation of ERK1 and ERK2 cascade GO Biological Processes -34.9831828 64 More
GO:0070723 response to cholesterol GO Biological Processes -8.11481650 11 More
GO:0070848 response to growth factor GO Biological Processes -40.6139195 102 More
GO:0070920 regulation of production of small RNA involved in gene silencing by RNA GO Biological Processes -5.08699974 5 More
GO:0071216 cellular response to biotic stimulus GO Biological Processes -28.1549742 59 More
GO:0071219 cellular response to molecule of bacterial origin GO Biological Processes -28.3848077 56 More
GO:0071222 cellular response to lipopolysaccharide GO Biological Processes -26.0381191 52 More
GO:0071363 cellular response to growth factor stimulus GO Biological Processes -39.8883675 98 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0071407 cellular response to organic cyclic compound GO Biological Processes -19.6857751 39 More
GO:0071559 response to transforming growth factor beta GO Biological Processes -17.0634996 37 More
GO:0071560 cellular response to transforming growth factor beta stimulus GO Biological Processes -16.8909657 36 More
GO:0071772 response to BMP GO Biological Processes -7.7216264 19 More
GO:0071773 cellular response to BMP stimulus GO Biological Processes -7.7216264 19 More
GO:0071900 regulation of protein serine/threonine kinase activity GO Biological Processes -19.5794055 63 More
GO:0071902 positive regulation of protein serine/threonine kinase activity GO Biological Processes -13.5008002 23 More
GO:0072175 epithelial tube formation GO Biological Processes -6.28242122 20 More
GO:0072521 purine-containing compound metabolic process GO Biological Processes -2.16218573 11 More
GO:0072562 blood microparticle GO Cellular Components -39.0217600 39 More
GO:0085029 extracellular matrix assembly GO Biological Processes -5.21154381 9 More
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO Biological Processes -13.1150464 44 More
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO Biological Processes -10.5573443 25 More
GO:0090218 positive regulation of lipid kinase activity GO Biological Processes -5.34310134 6 More
GO:0090263 positive regulation of canonical Wnt signaling pathway GO Biological Processes -2.20870076 11 More
GO:0090287 regulation of cellular response to growth factor stimulus GO Biological Processes -21.1381780 60 More
GO:0090316 positive regulation of intracellular protein transport GO Biological Processes -2.57210479 7 More
GO:0090322 regulation of superoxide metabolic process GO Biological Processes -9.31154255 13 More
GO:0090407 organophosphate biosynthetic process GO Biological Processes -3.52771570 18 More
GO:0090594 inflammatory response to wounding GO Biological Processes -8.11856573 7 More
GO:0097190 apoptotic signaling pathway GO Biological Processes -11.7839485 23 More
GO:0097191 extrinsic apoptotic signaling pathway GO Biological Processes -9.74858067 13 More
GO:0097305 response to alcohol GO Biological Processes -17.4096682 46 More
GO:0097709 connective tissue replacement GO Biological Processes -4.82387082 4 More
GO:0098858 actin-based cell projection GO Cellular Components -2.23189213 18 More
GO:0110149 regulation of biomineralization GO Biological Processes -10.9748263 24 More
GO:0110150 negative regulation of biomineralization GO Biological Processes -8.31494447 8 More
GO:0110151 positive regulation of biomineralization GO Biological Processes -4.74345761 11 More
GO:1900180 regulation of protein localization to nucleus GO Biological Processes -3.85830967 16 More
GO:1900182 positive regulation of protein localization to nucleus GO Biological Processes -4.19203093 7 More
GO:1900368 regulation of post-transcriptional gene silencing by RNA GO Biological Processes -6.88005887 12 More
GO:1900369 negative regulation of post-transcriptional gene silencing by RNA GO Biological Processes -7.60090654 9 More
GO:1900370 positive regulation of post-transcriptional gene silencing by RNA GO Biological Processes -3.60377864 4 More
GO:1901136 carbohydrate derivative catabolic process GO Biological Processes -3.37180259 9 More
GO:1901293 nucleoside phosphate biosynthetic process GO Biological Processes -1.83737953 8 More
GO:1901654 response to ketone GO Biological Processes -10.4509771 32 More
GO:1901861 regulation of muscle tissue development GO Biological Processes -2.53742702 7 More
GO:1902105 regulation of leukocyte differentiation GO Biological Processes -18.8286876 32 More
GO:1902107 positive regulation of leukocyte differentiation GO Biological Processes -14.6775052 22 More
GO:1902893 regulation of miRNA transcription GO Biological Processes -10.5909336 18 More
GO:1902895 positive regulation of miRNA transcription GO Biological Processes -9.50703189 15 More
GO:1903053 regulation of extracellular matrix organization GO Biological Processes -8.17680088 15 More
GO:1903054 negative regulation of extracellular matrix organization GO Biological Processes -8.11586193 6 More
GO:1903055 positive regulation of extracellular matrix organization GO Biological Processes -4.01585848 7 More
GO:1903076 regulation of protein localization to plasma membrane GO Biological Processes -2.83846671 6 More
GO:1903510 mucopolysaccharide metabolic process GO Biological Processes -2.64314024 10 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1903706 regulation of hemopoiesis GO Biological Processes -16.2759166 33 More
GO:1903708 positive regulation of hemopoiesis GO Biological Processes -14.6775052 22 More
GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA GO Biological Processes -5.19429515 5 More
GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA GO Biological Processes -4.31351457 5 More
GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA GO Biological Processes -5.05315969 4 More
GO:1903828 negative regulation of protein localization GO Biological Processes -8.86943289 30 More
GO:1903829 positive regulation of protein localization GO Biological Processes -12.9651258 57 More
GO:1903844 regulation of cellular response to transforming growth factor beta stimulus GO Biological Processes -8.41113232 25 More
GO:1904375 regulation of protein localization to cell periphery GO Biological Processes -3.14645923 7 More
GO:1904892 regulation of receptor signaling pathway via STAT GO Biological Processes -12.9980471 24 More
GO:1904894 positive regulation of receptor signaling pathway via STAT GO Biological Processes -11.2917234 16 More
GO:1904951 positive regulation of establishment of protein localization GO Biological Processes -13.0308630 46 More
GO:1905207 regulation of cardiocyte differentiation GO Biological Processes -9.12694220 13 More
GO:1905209 positive regulation of cardiocyte differentiation GO Biological Processes -9.78130162 11 More
GO:1905314 semi-lunar valve development GO Biological Processes -10.3278393 15 More
GO:1905475 regulation of protein localization to membrane GO Biological Processes -3.01117711 17 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000377 regulation of reactive oxygen species metabolic process GO Biological Processes -19.1025541 38 More
GO:2000379 positive regulation of reactive oxygen species metabolic process GO Biological Processes -15.0445998 16 More
GO:2000637 positive regulation of miRNA-mediated gene silencing GO Biological Processes -3.67847337 4 More
GO:2000677 regulation of transcription regulatory region DNA binding GO Biological Processes -4.46569153 6 More
GO:2000679 positive regulation of transcription regulatory region DNA binding GO Biological Processes -4.37707433 7 More
GO:2000725 regulation of cardiac muscle cell differentiation GO Biological Processes -3.64344566 6 More
KEGG pathways: 33 records
KEGG Description Category LogP Number of genes Detail
hsa04010 MAPK signaling pathway KEGG Pathway -13.6331973 26 More
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04068 FoxO signaling pathway KEGG Pathway -6.87449445 21 More
hsa04218 Cellular senescence KEGG Pathway -5.14633043 11 More
hsa04350 TGF-beta signaling pathway KEGG Pathway -6.45304971 17 More
hsa04380 Osteoclast differentiation KEGG Pathway -7.05199617 21 More
hsa04390 Hippo signaling pathway KEGG Pathway -3.46529255 17 More
hsa04659 Th17 cell differentiation KEGG Pathway -9.80516906 14 More
hsa04672 Intestinal immune network for IgA production KEGG Pathway -7.87779205 9 More
hsa04926 Relaxin signaling pathway KEGG Pathway -10.8215200 16 More
hsa04932 Non-alcoholic fatty liver disease KEGG Pathway -11.2628136 17 More
hsa04933 AGE-RAGE signaling pathway in diabetic complications KEGG Pathway -25.8646207 26 More
hsa05140 Leishmaniasis KEGG Pathway -12.4439861 14 More
hsa05142 Chagas disease KEGG Pathway -21.3868632 23 More
hsa05144 Malaria KEGG Pathway -31.5561809 24 More
hsa05145 Toxoplasmosis KEGG Pathway -13.6215025 17 More
hsa05146 Amoebiasis KEGG Pathway -14.8474637 18 More
hsa05152 Tuberculosis KEGG Pathway -14.5221547 22 More
hsa05161 Hepatitis B KEGG Pathway -5.78517620 12 More
hsa05166 Human T-cell leukemia virus 1 infection KEGG Pathway -5.08552863 13 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05205 Proteoglycans in cancer KEGG Pathway -18.5545131 27 More
hsa05210 Colorectal cancer KEGG Pathway -3.02613520 11 More
hsa05211 Renal cell carcinoma KEGG Pathway -1.89318511 4 More
hsa05212 Pancreatic cancer KEGG Pathway -2.89550682 10 More
hsa05220 Chronic myeloid leukemia KEGG Pathway -2.89550682 10 More
hsa05225 Hepatocellular carcinoma KEGG Pathway -5.07719186 21 More
hsa05226 Gastric cancer KEGG Pathway -5.33653529 20 More
hsa05321 Inflammatory bowel disease KEGG Pathway -16.3800424 16 More
hsa05323 Rheumatoid arthritis KEGG Pathway -22.3868189 23 More
hsa05410 Hypertrophic cardiomyopathy KEGG Pathway -9.74858067 13 More
hsa05414 Dilated cardiomyopathy KEGG Pathway -7.04373804 18 More
hsa05415 Diabetic cardiomyopathy KEGG Pathway -11.4800633 20 More
Drug-Gene interaction
view
Related drugs: 37 records
Drug name Interaction type Source PMID View
adriamycin NCI 10203574 view
amifostine NCI 12005544 view
aspirin PharmGKB 19138248 view
atenolol NCI 15049387 view
cladribine NCI 12097998 view
disitertide TTD 24393789 view
doxorubicin NCI 12956904 view
emodin NCI 11887862 view
etoposide NCI 16002781 view
fenretinide NCI 8993839 view
fresolimumab antibodyinhibitor TALCChemblInteractions view
genistein NCI 12580099 view
gossypol NCI 15015581 view
hydrocortisone NCI 7895901 view
inositol NCI 8013389 view
irinotecan PharmGKB 27160286 view
ly-2382770 inhibitor ChemblInteractions view
m-7824 TTD view
melatonin NCI 9649124 view
metelimumab inhibitor ChemblInteractions view
nicotine NCI 10198208 view
nis-793 TTD view
pioglitazone NCI 17407709 view
pirfenidone NCITTD 12907346 view
ramipril NCI 15716710 view
rituximab PharmGKB 22129793 view
sandostatin NCI 12142738 view
silybin a NCI 15103051 view
sotatercept TTD view
streptozocin NCI 17968528 view
tamoxifen NCI 8019941 view
testosterone NCI 9288184 view
toremifene NCI 12476040 view
triamcinolone NCI 12174062 view
vactosertib TTD view
verapamil NCI view
vitamin e NCI 9608545 view
Related studies: 26 records
Molecular factor Omics type Application Objective MI type Reference
NM_000660.7:c.29C>T genomics myocardial infarction[diagnosis] myocardial infarction Yokota M et al. Circulation. 2000
NM_000660.7:c.74G>C genomics acute myocardial infarction[diagnosis] acute myocardial infarction Najar RA et al. Am J Med Sci. 2011
NM_000660.7:c.788C>T genomics acute myocardial infarction[diagnosis] acute myocardial infarction Najar RA et al. Am J Med Sci. 2011
NM_000660.7:c.74G>C genomics myocardial infarction[diagnosis] myocardial infarction Wu L et al. Biosci Rep. 2019
NM_000660.7:c.[-509C>T;29C>T;74G>C;788C>T] genomics myocardial infarction[diagnosis] myocardial infarction Koch W et al. Arterioscler Thromb Vasc Biol. 2006
NM_030578.4:c.[*18G>A;-509C>T;29C>T] genomics acute myocardial infarction[diagnosis] acute myocardial infarction Crobu F et al. BMC Med Genet. 2008
NM_000660.7:c.[-509C>T;29C>T] genomics myocardial infarction[diagnosis] myocardial infarction Barsova RM et al. Acta Naturae. 2012
transforming growth factor beta-1 proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Djurovic S et al. Nutr Metab Cardiovasc Dis. 1999
transforming growth factor beta-1 proteomics medium predictor acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Liu Z et al. Br J Biomed Sci. 2016
transforming growth factor beta-1 proteomics good predictor acute myocardial infarction[diagnosis] acute myocardial infarction Liu Z et al. Br J Biomed Sci. 2016
transforming growth factor beta-1 proteomics poor predictor acute non-ST elevation myocardial infarction[diagnosis] acute non-ST elevation myocardial infarction Liu Z et al. Br J Biomed Sci. 2016
transforming growth factor beta-1 proteomics atorvastatin plus bivalirudin[treatment (pharmacotherapy)] acute myocardial infarction Dong SH et al. Ann Palliat Med. 2020
NM_000660.7:c.74G>C genomics myocardial infarction[diagnosis] myocardial infarction Cambien F et al. Hypertension. 1996
NM_000660.7:c.-509C>T genomics myocardial infarction[diagnosis] myocardial infarction Koch W et al. Arterioscler Thromb Vasc Biol. 2006
NM_000660.7:c.29C>T genomics acute myocardial infarction[diagnosis] acute myocardial infarction Najar RA et al. Am J Med Sci. 2011
NM_000660.7:c.-509C>T genomics acute myocardial infarction[diagnosis] acute myocardial infarction Najar RA et al. Am J Med Sci. 2011
NM_000660.7:c.29C>T genomics myocardial infarction[diagnosis] myocardial infarction Chen Y et al. Arthritis Res Ther. 2012
NM_000660.7:c.29C>T genomics myocardial infarction[diagnosis] myocardial infarction Barsova RM et al. Acta Naturae. 2012
NM_000660.7:c.29C>T genomics myocardial infarction[diagnosis] myocardial infarction Barsova RM et al. Acta Naturae. 2012
NM_000660.7:c.-509C>T genomics myocardial infarction[diagnosis] myocardial infarction Barsova RM et al. Acta Naturae. 2012
NM_000660.7:c.-509C>T genomics myocardial infarction[diagnosis] myocardial infarction Barsova RM et al. Acta Naturae. 2012
NM_000660.7:c.-509C>T genomics recurrent myocardial infarction[prognosis (bad)] myocardial infarction Barsova RM et al. Acta Naturae. 2012
NM_000660.7:c.74G>C genomics myocardial infarction[diagnosis] myocardial infarction Barsova RM et al. Acta Naturae. 2012
NM_000660.7:c.29C>T genomics acute myocardial infarction[diagnosis] acute myocardial infarction Barsova RM et al. PLoS One. 2015
NM_000660.7:c.29C>T genomics acute myocardial infarction[diagnosis] acute myocardial infarction Barsova RM et al. PLoS One. 2015
NM_000660.7:c.74G>C genomics myocardial infarction[diagnosis] myocardial infarction Osmak GJ et al. Russian. 2020
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